Traditional pluripotent stem cells are grown as adherent cultures, with limited and expensive scalability.Accellta solves the scale-up and cost challenges of stem cell culturing using the Maxells™ and Singles solutions.
Maxells™ are stem cells cultured as cell clusters devoid of feeder cells without micro-carriers. Using dynamic bioreactors, Maxells™ provides a vastly cost-effective means to expand stem cells in customized quantities.
Maxells™ delivers unprecedented magnitude and quality. Based on proprietary protocols developed by Accellta, Maxells technology can be applied to create both research-grade as well as clinical-grade feeder-free xeno-free cultures. In addition, Accellta developed proprietary protocols for the differentiation of the Maxells directly in suspension to a variety of cell types (e. g., MSCs. HSCs, NPs, CMs)

• Cell concentration: >20 million cells/ml
• Expansion factor: X30-35 in 11 days
• Suitable for undifferentiated pluripotent stem cells and progenitor cells
• Does not require enzymatic splitting
• Rock inhibitor-free, xeno-free defined medium
• Medium easily refreshed every two-three days
• Straightforward perfusion process in bioreactors
• Easy transition from suspension culture back to adherent culture
• Feeder cell-free
• Homogenous exposure to medium’s nutrients
• >95% of cells are pluripotent; <5% spontaneous differentiation
• Karyotype stability
• High viability rate
• Methods for directed differentiation in suspension